Corona Precaution Dose: In India, now the precaution dose of corona vaccine for health workers, frontline workers and those above 60 years is about to start. The government has now made it clear that the precaution dose will be the same as in the earlier two doses. That is, no mixing will be done. The one who has received two doses of Covaxin will also get the precaution dose of Covaxin. Those who have received two doses of Covishield will receive a preconception dose of Covishield.
Mixed vaccine means that the beneficiary is given doses of vaccines from different companies. Its purpose is to increase the efficacy of the vaccine and the protection it provides. It is also called interchangeability and interchangeable dosage regimen. Interchangeable dosage regimens are also being used in many countries including the US. Study is going on in India on this.
There have been many studies on mixed vaccines, in which the dose of mixed vaccine is being said to be more effective. The European Medicines Agency (EMA) and the European Center for Disease Prevention and Control (ECDC) said in a joint statement that the combination of vector and mRNA vaccines may provide better protection against the coronavirus.
According to the study published in the Lancet journal, giving a second dose of Novavax or Moderna nine weeks after the first dose of AstraZeneca or Pfizer can help build up stronger immunity in the body.
NITI Aayog member Dr VK Paul has said that the details of data and science of mixing vaccines will be looked at and will be escalated on a balanced approach.
According to medical experts, there are apprehensions about vaccine mixing in foreign countries as well, but so far no such evidence has been found that mixing has side effects. For example, China-made Sinovac is being followed by Pfizer’s booster shot in Malaysia, but many people are not coming to get the booster because of the fear of side effects.
Respiratory expert Dr. Helmi Myedin has said that research done in Europe has shown that people taking mixed vaccine are 68 percent less likely to have symptomatic infection. Other vaccines are being used for booster injections in the US.
A study conducted at AIG Hospital, Hyderabad in India has claimed that 4 times more antibodies are being produced when each dose of Kovishield and Kovishield vaccine is mixed and matched. Experts of the hospital have suggested that applying a mixed vaccine in the preconception dose vaccination starting from January 10 will be of more benefit against the epidemic. In this study, it was found that in those who had received the mixed vaccine, antibodies against Corona AK were four times more.